If you’ve been feeling stuck in your weight loss journey—like your body just isn’t responding no matter how clean you eat or how hard you train—you’re not crazy. You’re likely fighting biology, not just bad habits. And that’s exactly where medical weight loss therapies like GLP-1, GIP, and GLP-3 come in.
These aren’t buzzwords. They’re powerful, clinically backed treatments that target the root cause of weight gain: your hormones, your gut-brain signaling, and your metabolic thermostat.
What Are GLP-1, GIP, and GLP-3?
Let’s break it down—quick and dirty:
- GLP-1 (Glucagon-Like Peptide-1): Naturally secreted in your gut, GLP-1 slows gastric emptying, reduces appetite, increases insulin secretion, and stabilizes blood sugar. Medications like Semaglutide (Ozempic, Wegovy) are GLP-1 receptor agonists. Translation? You feel fuller, longer—and your cravings drop off a cliff.
- GIP (Glucose-Dependent Insulinotropic Polypeptide): This hormone works in synergy with GLP-1 to enhance insulin release and improve blood sugar regulation. Tirzepatide (Mounjaro, Zepbound) combines GLP-1 + GIP for a one-two punch that crushes appetite and improves metabolic function.
- GLP-3 (Glucagon-Like Peptide-2/3): This lesser-known gut hormone—often grouped with GLP-2—plays a critical role in gut barrier repair, nutrient absorption, and intestinal growth. It’s being studied for its powerful regenerative effects on the GI tract, especially in patients with chronic inflammation, leaky gut, or poor nutrient uptake (which means your body isn’t absorbing the vitamins, minerals, and macronutrients from your food efficiently—even if you're eating clean).
Two notable compounds stand out:
- Teduglutide (brand name Gattex): FDA-approved for short bowel syndrome, used off-label for gut healing and digestive optimization.
- Retatrutide (in clinical trials): A next-gen triple agonist that activates GLP-1, GIP, and GLP-2/3 pathways. Early data shows unprecedented fat loss, enhanced glucose control, and improved GI function—all in one molecule. Retatrutide is poised to reshape the future of medical weight loss.
Why You’re Not Losing Weight (and How This Fixes It)
Here’s the real talk: chronic stress, sleep disruption, and yo-yo dieting can wreck your body’s ability to regulate appetite and insulin. Your brain stops “hearing” your gut. GLP-1, GIP, and GLP-3 reset that communication line—allowing your body to finally respond.
These peptides:
- Rewire your hunger cues
- Enhance insulin sensitivity
- Support fat loss without muscle loss
- Regulate your metabolism, even during sleep
- Improve digestion and nutrient utilization (GLP-3’s specialty)
At Evolve Anti-Aging & Wellness, we combine these therapies with comprehensive lab work, genetic testing, nutrient IVs, and hormone balancing—so you’re not just losing weight, you’re upgrading your biology.
Who Benefits from GLP Treatments?
If any of this sounds like you, you’re a candidate:
- You’ve hit a plateau and can’t break it
- You’ve struggled with emotional eating or blood sugar crashes
- You’re post-menopausal or experiencing hormonal shifts
- You’ve tried everything and nothing sticks
- You want to burn fat without losing muscle
These aren’t magic injections—they’re strategic tools backed by science and personalized to your body’s unique needs.
Why Evolve Is Different
We don’t prescribe and pray.
We test, tailor, and track.
Your GLP-based plan is just the start. Want to go deeper? You can upgrade with hormone optimization, gut health repair, genetic insights, and IV nutrient support—all offered in-house, and all backed by actual science, not “wellness fairy dust.”
We built this place to cut through the noise. No guesswork. No gimmicks. Just results.
Start Your GLP Protocol Today
Want to find out if GLP-1, GIP, or GLP-3 is right for you?
We’ll draw your labs, assess your full metabolic profile, and give you the real answers—no fluff, no hype. Just results.