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A Revolution in Full-Body Cellular Detox & Optimization

Eboo Therapy in Encino, CA

EBOO—Extracorporeal Blood Oxygenation and Ozonation—is the most advanced form of medical ozone therapy available today. Unlike traditional IV ozone methods, EBOO filters and recirculates your blood through a medical-grade dialysis membrane while simultaneously infusing it with medical ozone and oxygen. Appropriateness is determined through clinical evaluation and diagnostic findings.

WHAT IS EBOO

A modern approach to wellness optimization

EBOO (Extracorporeal Blood Oxygenation and Ozonation) is a blood conditioning procedure in which blood is circulated outside the body, exposed to medical-grade ozone and oxygen, and returned in a controlled clinical setting. At Evolve, it is considered only as part of a broader, individualized care plan.

This therapy is performed in a controlled clinical environment as part of a broader wellness or optimization plan.

Easy, Safe & Effective

How the process works

Pricing

EBOO therapy is delivered as part of a medically supervised protocol designed to support cellular health, circulation, and detoxification pathways.

Treatment plans may vary depending on clinical goals and physician guidance.

Single Session

$1,250

  • One EBOO therapy session
  • Medical supervision throughout treatment
  • Integrated into your personalized wellness plan

Three-Session Protocol

$3,000

Many patients choose a structured protocol to allow the body to progressively respond to therapy.

  • Three EBOO therapy sessions
  • Recommended scheduling for optimal response
  • Ongoing clinical oversight from the Evolve team
  • Any IV Therapy of choice included during treatment (does not include NAD+)

Our medical team will determine whether EBOO therapy is appropriate for your treatment plan.

About

Clinical context & current evidence

Research on EBOO therapy is evolving, and clinical use varies across settings. At Evolve, decisions regarding EBOO are made conservatively, based on individual health status, goals, and overall treatment strategy.

EBOO therapy is discussed openly and responsibly at Evolve Anti-Aging. We do not promise specific disease outcomes or guaranteed results.

Instead, EBOO is considered as part of a broader, personalized strategy that may include metabolic optimization, peptide support, hormone balance, and recovery-focused nutrition. Current scientific literature on EBOO is evolving, with early findings that are promising but still limited in scope.

We are transparent about what is currently understood, what remains under investigation, and where ongoing research continues to explore potential applications.

Early clinical research

Early studies describe EBOO as a controlled oxygen–ozone administration through extracorporeal circulation. In one 2005 review, researchers discussed treating up to ~4.8 liters of blood per session over about 60 minutes, reporting predictable short-term changes in oxidative-stress markers and general tolerance across more than 1,200 treatments.

Comparative clinical signals

In a small randomized trial comparing EBOO to IV prostacyclin in patients with peripheral artery disease, sessions involving EBOO were associated with improvement in skin lesions and symptoms without changes in arterial circulation measures. These results were condition-specific and preliminary, emphasizing the need for larger studies.

Observations and mechanisms

Research notes that controlled oxidative stimuli—such as oxygen–ozone exposure—may influence redox balance, inflammatory pathways, and metabolic factors. Published reports highlight that EBOO procedural parameters (e.g., ozone dose, blood flow rates) and safety monitoring are critical, while long-term effects remain understudied and require further investigation.

EBOO is ideal for individuals who suffer from:

Who may consider EBOO therapy

EBOO therapy may be considered for individuals seeking additional support for recovery, energy, or physiological stress when integrated within a comprehensive care plan.

This therapy is most often discussed with patients who are experiencing:

Fatigue or recovery challenges

Persistent low energy, mental fog, or prolonged recovery can affect how the body adapts to physical and metabolic stress. In these situations, EBOO may be evaluated as part of a broader plan focused on restoring balance, supporting physiological efficiency, and improving overall resilience under medical supervision.

Chronic physiological stress

Ongoing internal stressors—whether metabolic, environmental, or lifestyle-related—can leave the body operating in a sustained state of strain. EBOO may be considered within a physician-led strategy aimed at supporting recovery pathways and overall system regulation, rather than as a standalone intervention.

Signs of reduced cellular efficiency

Changes in energy, recovery capacity, and mental clarity are not always attributable to aging alone. In some cases, these shifts reflect changes in how the body manages energy, repair, and adaptation. EBOO may be discussed as part of a broader optimization approach that includes nutrition, metabolic support, hormone balance, and other physician-guided therapies.

EBOO therapy is not appropriate for everyone. A consultation with our medical team is required to review health history, goals, and determine whether this therapy aligns with your individual care plan.

How EBOO fits into your care plan

EBOO therapy is not used in isolation. At Evolve Anti-Aging, it may be incorporated into a broader strategy that can include diagnostic evaluation, hormone balance, peptide therapy, lifestyle optimization, and recovery protocols.

The role of EBOO—if appropriate—is determined through medical evaluation and adjusted based on individual goals, response, and overall health considerations.

Need help?

Frequently Asked Questions

About EBOO Therapy

Safety & Medical Oversight

What to Expect

Treatment Planning & Integration

Visiting Our Encino Clinic

Explore whether EBOO therapy is right for you

Schedule a consultation to determine whether EBOO therapy aligns with your health goals and overall care plan.