WHAT IS EBOO
A modern approach to wellness optimization
EBOO (Extracorporeal Blood Oxygenation and Ozonation) is a blood conditioning procedure in which blood is circulated outside the body, exposed to medical-grade ozone and oxygen, and returned in a controlled clinical setting. At Evolve, it is considered only as part of a broader, individualized care plan.
This therapy is performed in a controlled clinical environment as part of a broader wellness or optimization plan.
Easy, Safe & Effective
How the process works
You’ll undergo a detailed intake and medical screening. Labs may be required before treatment.
Two IV lines are placed: one draws blood, the other reinfuses it after passing through the EBOO circuit. A dialysis-grade filter captures waste, and the system applies oxygen, ozone, and UV exposure under careful medical oversight.
The full session typically takes 60–90 minutes, including setup and monitoring.
Afterwards, your medical team reviews what was done and how it may integrate into your overall wellness plan.
Pricing
EBOO therapy is delivered as part of a medically supervised protocol designed to support cellular health, circulation, and detoxification pathways.
Treatment plans may vary depending on clinical goals and physician guidance.
Single Session
$1,250
- One EBOO therapy session
- Medical supervision throughout treatment
- Integrated into your personalized wellness plan
Three-Session Protocol
$3,000
Many patients choose a structured protocol to allow the body to progressively respond to therapy.
- Three EBOO therapy sessions
- Recommended scheduling for optimal response
- Ongoing clinical oversight from the Evolve team
- Any IV Therapy of choice included during treatment (does not include NAD+)
Our medical team will determine whether EBOO therapy is appropriate for your treatment plan.
About
Clinical context & current evidence
Research on EBOO therapy is evolving, and clinical use varies across settings. At Evolve, decisions regarding EBOO are made conservatively, based on individual health status, goals, and overall treatment strategy.
EBOO therapy is discussed openly and responsibly at Evolve Anti-Aging. We do not promise specific disease outcomes or guaranteed results.
Instead, EBOO is considered as part of a broader, personalized strategy that may include metabolic optimization, peptide support, hormone balance, and recovery-focused nutrition. Current scientific literature on EBOO is evolving, with early findings that are promising but still limited in scope.
We are transparent about what is currently understood, what remains under investigation, and where ongoing research continues to explore potential applications.
Early clinical research
Early studies describe EBOO as a controlled oxygen–ozone administration through extracorporeal circulation. In one 2005 review, researchers discussed treating up to ~4.8 liters of blood per session over about 60 minutes, reporting predictable short-term changes in oxidative-stress markers and general tolerance across more than 1,200 treatments.
Comparative clinical signals
In a small randomized trial comparing EBOO to IV prostacyclin in patients with peripheral artery disease, sessions involving EBOO were associated with improvement in skin lesions and symptoms without changes in arterial circulation measures. These results were condition-specific and preliminary, emphasizing the need for larger studies.
Observations and mechanisms
Research notes that controlled oxidative stimuli—such as oxygen–ozone exposure—may influence redox balance, inflammatory pathways, and metabolic factors. Published reports highlight that EBOO procedural parameters (e.g., ozone dose, blood flow rates) and safety monitoring are critical, while long-term effects remain understudied and require further investigation.
EBOO is ideal for individuals who suffer from:
Who may consider EBOO therapy
EBOO therapy may be considered for individuals seeking additional support for recovery, energy, or physiological stress when integrated within a comprehensive care plan.
This therapy is most often discussed with patients who are experiencing:

Fatigue or recovery challenges
Persistent low energy, mental fog, or prolonged recovery can affect how the body adapts to physical and metabolic stress. In these situations, EBOO may be evaluated as part of a broader plan focused on restoring balance, supporting physiological efficiency, and improving overall resilience under medical supervision.

Chronic physiological stress
Ongoing internal stressors—whether metabolic, environmental, or lifestyle-related—can leave the body operating in a sustained state of strain. EBOO may be considered within a physician-led strategy aimed at supporting recovery pathways and overall system regulation, rather than as a standalone intervention.

Signs of reduced cellular efficiency
Changes in energy, recovery capacity, and mental clarity are not always attributable to aging alone. In some cases, these shifts reflect changes in how the body manages energy, repair, and adaptation. EBOO may be discussed as part of a broader optimization approach that includes nutrition, metabolic support, hormone balance, and other physician-guided therapies.
EBOO therapy is not appropriate for everyone. A consultation with our medical team is required to review health history, goals, and determine whether this therapy aligns with your individual care plan.
How EBOO fits into your care plan
EBOO therapy is not used in isolation. At Evolve Anti-Aging, it may be incorporated into a broader strategy that can include diagnostic evaluation, hormone balance, peptide therapy, lifestyle optimization, and recovery protocols.
The role of EBOO—if appropriate—is determined through medical evaluation and adjusted based on individual goals, response, and overall health considerations.
Need help?
Frequently Asked Questions
About EBOO Therapy
EBOO therapy (Extracorporeal Blood Oxygenation and Ozonation) is an advanced blood conditioning procedure performed in a clinical setting under medical supervision. Blood is circulated through a specialized system and returned to the body as part of a physician-guided care plan.
EBOO stands for Extracorporeal Blood Oxygenation and Ozonation. It refers to a process in which blood is temporarily circulated outside the body through a specialized medical system before being reinfused under physician supervision.
EBOO therapy is not FDA-approved to diagnose, treat, cure, or prevent any disease. Information provided is for educational purposes and to support informed discussions with a medical professional.
Safety & Medical Oversight
EBOO therapy has been described in clinical and observational settings with an emphasis on feasibility and procedural tolerance when performed under controlled conditions. At Evolve Anti-Aging, EBOO therapy is performed with medical oversight and continuous monitoring to prioritize safety.
At Evolve Anti-Aging, EBOO therapy is performed in a clinical setting under the supervision of a medical team. A consultation is required prior to treatment to determine appropriateness.
What to Expect
An EBOO therapy session involves circulating blood through a specialized medical system before returning it to the body. Sessions are conducted in-clinic with medical supervision and continuous monitoring.
A typical EBOO therapy visit lasts approximately 60–90 minutes, including setup, monitoring, and post-session review.
Individual responses vary. Some people report changes in energy or clarity, while others notice minimal immediate effects. EBOO therapy is discussed as part of a broader care plan rather than a treatment with guaranteed outcomes.
Treatment Planning & Integration
There is no standard number of EBOO therapy sessions. If appropriate, recommendations are determined during consultation based on individual goals, health considerations, and how EBOO may fit into a broader care plan.
No. At Evolve Anti-Aging, EBOO therapy is evaluated as part of a comprehensive, physician-guided care strategy and not as a standalone solution.
If appropriate, EBOO therapy may be discussed alongside other physician-guided approaches such as metabolic optimization, hormone balance, peptide-based therapies, or recovery-focused nutrition.
Visiting Our Encino Clinic
EBOO therapy is offered at Evolve Anti-Aging in Encino, California, under medical supervision. Patients visit from Encino and surrounding areas throughout the San Fernando Valley and greater Los Angeles.
Yes. A consultation is required before scheduling EBOO therapy at our Encino clinic to review health history and determine whether the therapy aligns with your care plan.
Explore whether EBOO therapy is right for you
Schedule a consultation to determine whether EBOO therapy aligns with your health goals and overall care plan.

